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Fluorine in the Life Science Industry

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Contents	90	Contents - Inhalt - Sommaire
Editorial	92	Fascination Fluorine
	93	The Importance of Fluorine in the Life Science Industry P. Maienfisch*, R.G. Hall
	100	Simple and Efficient Industrial Preparation of Various Trifluoromethyl Ketones and Derivatives D. Michel
	104	Chemo-Enzymatic Synthesis of Chiral Fluorine-Containing Building Blocks R.H. Blaauw*, D.R. IJzendoorn, J.G.O. Cremers, F.P.J.T. Rutjes, Q.B. Broxterman, H.E. Schoemaker
	108	gem-Difluorovinyl Derivatives as Insecticides and Acaricides T. Pitterna*, M. Böger, P. Maienfisch
	117	Changes in the Activity and Selectivity of Herbicides by Selective Fluorine Substitution, Taking Bentranil and Classic® Analogues as Examples G. Hamprecht*, B. Würzer, M. Witschel
	123	Fluorine-Substitution in Cholesteryl Ester Transfer Protein Inhibitors (CETP-Inhibitors) – Biology, Chemistry, SAR, and Properties H. Paulsen*, C. Schmeck, A. Brandes, G. Schmidt, J. Stoltefuss, S.N. Wirtz, M. Lögers, P. Naab, K.-D. Bremm, H. Bischoff, D. Schmidt, S. Zaiss, S. Antons
	128	Influence of Fluorination at Position 16 of Antibacterial Pristinamycins II E. Bacqué
	133	α-Fluoro-Benzylphosphonates as Reagents for the Preparation of 1-Fluoro-1-Aryl Alkenes and α-Fluorostilbenes T. Allmendinger*, R. Fujimoto, F. Gasparini, W. Schilling, Y. Satoh
	138	Synthesis of Some Arylsulfur Pentafluoride Pesticides and Their Relative Activities Compared to the Trifluoromethyl Analogues P.J. Crowley, G. Mitchell, R. Salmon*, P.A. Worthington
	143	Bioisosterism of Fluorine and Cyano as Indole Substituents.Theoretical, in vitro and in vivo Examination T. Heinrich*, H. Böttcher, G.D. Bartoszyk, H. Schwartz, S. Anzali, J. März, H.E. Greiner, C.A. Seyfried
	148	Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors Y. Matsumura*, T. Nakano, N. Mori, Y. Morizawa
	153	Perfluorinated Brønsted ‘Superacids’: Powerful Catalysts for the Preparation of Vitamin E T. Netscher*, W. Bonrath, A. Haas, E. Hoppmann, H. Pauling
	156	Selective Synthesis of Fluorinated Compounds: Process Development and Preparation of Fluorinated Compounds from Gram up to Kilogram Scale H. Steiner*, H. Meier
	159	Microfluidics-Based Reactors for Safe Fluorinations Using Elemental Fluorine M.D. Turnbull*, N.B. Carter, S. Dennison, J. Deacon, R. Holley
Conference Reports	163	abc Technologies 2004, Basel (Switzerland), January 22–23, 2004
SCG/SSC/SCS	166	Var. Informations
information	170	News, Lectures, Congresses - Conferences - Workshops
CHIMIA-Report	173	CHIMIA-Report, 2004/03

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CHIMIA, Vol. 58, Issue 03/2004: Fluorine in the Life Science Industry

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