Pharmaceutical Industry in Switzerland 2004 09

Scientific Content

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Contents

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Editorial

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Icon OpenAccessContent  Icon ExternalLinkMolecular Informatics as an Enabling in silico Technology Platform for Drug Discovery
E. Jacoby*, A. Schuffenhauer, M. Popov, K. Azzaoui, E. Vangrevelinghe, J. Priestle, P. Ferrara, B. Faller, P. Acklin

 

585

Icon OpenAccessContent  Icon ExternalLinkSpeedScreen, a Label-Free, Affinity-Based High-Throughput Screening Technology for the Discovery of Orphan Protein Ligands
I. Filipuzzi 

 

588

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Lead Generation: Sowing the Seeds for Future Success
K.H. Bleicher, M. Nettekoven, J.-U. Peters, R. Wyler* 

 

 

601

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608

Icon OpenAccessContent  Icon ExternalLinkDrug Discovery in Oncology
C. García-Echeverría 

 

613

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Icon ExternalLink5-HT2C Receptor Agonists for the Treatment of Obesity. Biological and Chemical Adventures
D. Adams, A. Bénardeau, M.J. Bickerdike, J.M. Bentley, C. Bissantz, A. Bourson, I.A. Cliffe, P. Hebeisen, G.A. Kennett, A.R. Knight, C.S. Malcolm, J. Mizrahi, J.-M. Plancher*, H. Richter, S. Röver, S. Taylor, S.P. Vickers 

 

621

Icon OpenAccessContent  Icon ExternalLinkThe Synthetic Development of the Anti-Influenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu®): A Challenge for Synthesis & Process Research
S. Abrecht, P. Harrington, H. Iding, M. Karpf*, R. Trussardi, B. Wirz, U. Zutter 

 

630

Icon OpenAccessContent  Icon ExternalLink2-Styryl-pyridines and 2-(3,4-Dihydro-naphthalen-2-yl)-pyridines as Potent NR1/2B Subtype Selective NMDA Receptor Antagonists
B. Buettelmann*, A. Alanine, A. Bourson, R. Gill, M.-P. Heitz, V. Mutel, E. Pinard, G. Trube, R. Wyler 

 

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Inhibitors of Plasmepsin II – Potential Antimalarial Agents
C. Boss*, S. Richard-Bildstein, R. Furnari, J.-M. Bourgeois, O. Corminboeuf, C. Grisostomi, L. Coppex, L. Harris, L. Prade, S. Meyer, C. Binkert, W. Fischli, R. Brun, T. Weller 

 

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661

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Diverses

663

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SCG/SSC/SCS

664 Icon FreeContent 

Information

666

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CHIMIA-Report

667

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