SCG - DEV

Process Chemistry

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Contents	514	Table of Contents
Editorial	516	H. -R. Marti, J.S. Siegel
	518	Early Process Development: The Wyeth Approach M.K. O’Brien, M. Kolb, K. Sutherland, K. McCoy, A. Pilcher
	523	Process Development for Active Pharmaceutical Ingredients Following a Developmental Cascade C. Adler, J. Brunner, C. Fichtner, P. Küng, M.K. Levis, H.-R. Ruchti, A. Sjöberg, B. Weber*
	530	Process Development and Production Concepts for the Manufacturing of Organic Fine Chemicals at LONZA G. Heckmann, F. Previdoli, T. Riedel, D. Ruppen, D. Veghini*, U. Zacher
	534	Laboratory for Process Research – Ten Years of Successful Partnership between University of Zurich and the Pharmaceutical Industry T. Bader
	543	A General Approach to Indoles: Practical Applications for the Synthesis of Highly Functionalized Pharmacophores J.T. Kuethe
	554	Process Research and Scale-up of the κ-Opioid Receptor Agonist CJ-15,161 Drug Candidate B.M. Andresen, S. Caron, M. Couturier, K.M. DeVries, N.M. Do, K. Dupont-Gaudet, A. Ghosh, M. Girardin, J.M. Hawkins, T.M. Makowski, M. Riou, J.E. Sieser, J.L. Tucker, B.C. Vanderplas, T.J.N. Watson
	561	With Asymmetric Hydrogenation Towards a New, Enantioselective Synthesis of Orlistat R. Birk, M. Karpf, K. Püntener*, M. Scalone, M. Schwindt, U. Zutter
	566	The Formation of a Crystalline Oxazolidin-5-one from (l)-Alanine and its Use as a Chiral Template in the Practical Synthesis of α-Substituted Alanine Esters M. Eriksson*, E. Napolitano, J. Xu, S. Kapadia, D. Byrne, L. Nummy, N. Grinberg, S. Shen, H. Lee, V. Farina
	574	Recent Optimization Highlights of the Georgywood Process J.-P. Barras, B. Bourdin, F. Schröder*
	580	An Asymmetric Synthesis of PPAR-γ Agonist Navaglitazar from (+)-Methyl (2S,3R)-3-(4-methoxyphenyl)glycidate J.R. Rizzo T.Y. Zhang*
	584	The Chemical Development of CHIR-258 S. Zhu*, E. Harwood, S. Cai, X. Shang, G. Galvin, L. Jin, A. Yeung, B. Diaz, M. Zheng, D. Ryckman
	593	An Improved Process for Repaglinide via an Efficient and One Pot Process of (1S)-3-methyl-1- (2-piperidin-1-ylphenyl)butan-1-amine – A Useful Intermediate N. Kolla, C.R. Elati, P.J. Vankawala, S. Gangula, E. Sajja, Y. Anjaneyulu, A. Bhattacharya, V. Sundaram, V.T. Mathad*
	598	The Development of API Manufacturing Processes – Targets and Strategies D. Wieckhusen
	605	Data-Oriented Process Development: Determination of Reaction Parameters by Small-Scale Calorimetry with in situ Spectroscopy G. Puxty, U. Fischer, M. Jecklin, K. Hungerbühler*
	611	Cost Analysis of a Commercial Manufacturing Process of a Fine Chemical Compound using Micro Process Engineering U. Krtschil, V. Hessel*, D. Kralisch, G. Kreisel, M. Küpper, R. Schenk
	618	Continuous Chemistry in Microreaction Systems for Practical Use G. Müller, T. Gaupp, F. Wahl, G. Wille*
	623	Simulated Moving Bed Technology for the Industrial Small and Mid Scale Separation of Racemates P. Kaiser
	628	Process Research in the Ivory Tower N.S. Finney
	631	Using Bacteria to Quantify Arsenic Contamination in Potable Water J.R. van der Meer*, M. Berg, P.T.K. Trang
SCG/SSC/SCS	633	Ausserordentliche Generalversamlung der SCG
Information	634	News - Lectures - Conferences
CHIMIA-Report	636	CHIMIA - Report

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CHIMIA, Vol. 60, Issue 09/2006: Process Chemistry

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