SCG - DEV

From Chemical Research to Industrial Applications

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On February 6, 2009, a symposium entitled 'Frontiers in Bioorganic Chemistry' was held in honour of Prof. Daniel Bellus at the University of Basel. On that occasion the idea of a special issue of CHIMIA was conceived, with contributions from scientists who collaborated with Prof. Bellus during some point of their careers. The articles cover a wide range of research areas with the common denominator being chemistry. The title page shows an illustration from Robert Häner's article 'Nucleic Acids - Genes, Drugs, Molecular Lego and More' on chemically modified nucleic acids which find widespread use as tools in research, as diagnostic reagents and even as pharmaceutical compounds.

Additional content

Contents	2	Table of Contents
Information	4	CHIMIA News
Editorial	7	Prof. Beat Ernst, Dr. Gerardo Ramos
	8	Natural Products as Leads for Anticancer Drug Discovery: Discovery of New Chemotypes of Microtubule Stabilizers through Reengineering of the Epothilone Scaffold K.-H. Altmann*, F. Cachoux, F. Feyen, J. Gertsch, C. N. Kuzniewski, M. Wartmann
	14	Nucleic Acids – Genes, Drugs, Molecular Lego and More R. Häner
	17	From the Ganglioside GQ1bα to Glycomimetic Antagonists of the Myelin-Associated Glycoprotein (MAG) B. Ernst*, O. Schwardt, S. Mesch, M. Wittwer, G. Rossato, A. Vedani
	23	In vivo Neutralization of Naturally Existing Antibodies against Linear α(1,3)-Galactosidic Carbohydrate Epitopes by Multivalent Antigen Presentation: A Solution for the First Hurdle of Pig-to-Human Xenotransplantation R. O. Duthaler*, B. Ernst, R. Fischer, A. G. Katopodis, W. Kinzy, W. Marterer, R. Oehrlein,M. B. Streiff, G. Thoma
	29	Applications of Click Chemistry in Radiopharmaceutical Development J. C. Walsh, H. C. Kolb*
	34	The Design and Synthesis of Biologically Active Organophosphorus Compounds – The Role of a Central Research Laboratory R. G. Hall
	37	Host Marking Pheromone (HMP) in the Mexican Fruit Fly Anastrepha ludens A. J. F. Edmunds*, M. Aluja, F. Diaz-Fleischer, B. Patrian, L. Hagmann
	43	Continuous Non-Invasive Ophthalmic Glucose Sensor for Diabetics A. M. Domschke
	45	Para-Carboxy Modified Amphiphilic Calixarene, Self-Assembly and Interactions with Pharmaceutically-Relevant Molecules D. Elend, U. Pieles, P. Shahgaldian*
	49	Synthesis of Polypyrrole-Coated Core/Shell Nanoparticles A. Mühlebach, A. Hafner, F. Rime, K. Mpoukouvalas, L. Sun, J. Wang, G. Wegner, T. Beierlein
	56	Novel Thione-Thiol Rearrangement of Dithiocarbonic Acid O-(2,2,6,6-Tetramethylpiperidin-1-yl) Ester in the Context of Controlled Radical Polymerization P. Nesvadba*, L. Bugnon, T. Wagner
	59	Highly Enantioselective Catalytic Asymmetric Synthesis of a (R)-Sibutramin Precursor U. Berens, A. Hafner, O. Dosenbach, T. Tritschler, F. Schwarzenbach, H.-J. Kirner, C. Malan, O. Mai-Huynh
	65	Developing Catalysts and Catalytic Processes with Industrial Relevance H.-U. Blaser
	69	Closing Remarks at the Symposium in Honour of Daniel Belluš Pharmacenter, University of Basel, February 6, 2009 C. Ganter
	72	How Long is the Peer Review Process for Journal Manuscripts? A Case Study on Angewandte Chemie International Edition L. Bornmann*, H.-D. Daniel
	78	Bibliometrics as Weapons of Mass Citation La bibliométrie comme arme de citation massive A. Molinié, G. Bodenhausen
	90	The Follies of Citation Indices and Academic Ranking Lists A Brief Commentary to ‘Bibliometrics as Weapons of Mass Citation’ R. R. Ernst
Conference Reports	91	Biotech Research: Bringing Better Therapies to the People
SCG/SSC/SCS	95	Identification of Dioxin Metabolites in the Poisoning Case of Victor Yushchenko
	97	2010 SCNAT/SCS Chemistry Travel Award
	98	Jahresbericht 2009 der SCG
	107	Division of Analytical Chemistry: Weiterbildung Analytik
	108	Division of Medicinal Chemistry: Proteinase 2011
Information	110	News, Honors, Workshops, Conferences, Lectures
Diverses	114	EuCheMS Newsletter
CHIMIA-Report	118	Products, Services and News from Companies
Diverses	5	Instructions to Authors 2010
Diverses	1	Impressum

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CHIMIA, Vol. 64, Issue 01-02/2010: Chem. Research to Ind. Applications

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